Structure-activity relationships (SAR) analysis forms the bedrock in drug discovery. By systematically modifying the chemical structure of a lead compound and measuring the resulting biological activity, researchers can elucidate the key structural features responsible for potency. This understanding informs further optimization of novel therapeuti

Pharmacological profiling represents a crucial/essential/fundamental step in the development/synthesis/design of novel drug candidates. This process involves/encompasses/includes a comprehensive/thorough/systematic assessment of a drug's pharmacological/therapeutic/biochemical properties, aiming to elucidate/determine/identify its mechanism of acti